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Sciex CESI 8000 Plus ESI-MS System
With the CESI 8000 Plus system, you can effectively integrate high-efficiency capillary electrophoresis (CE) and electrospray ionization (ESI) into a single dynamic process within the same device.
Experience the revolutionary ESI-MS approach to discovering previously undetectable characteristics from the minutest amount of precious samples, faster than ever before. Whether using as a standalone capillary electrophoresis instrument or in conjunction with the power of mass spectrometry, the CESI 8000 Plus allows you to concentrate on your science rather than technology. You’ve worked hard to get your sample this far. Get the most from that precious material and hunt down the hidden information you couldn’t see before:
- Intact mAb charge variants with online MS detection
- Proteoforms & peptide PTMs such as those with multiple phosphorylation sites
- Challenging charged & polar metabolites/degradation products such as anionic and/or hydrophilic analytes
- Isobaric metabolites and glycans not resolved by traditional techniques
- Protein conformation and quantitation
| Key Features | |
|---|---|
| Zero Dead Volume | Single continuous separation capillary is contained within the OptiMS cartridge |
| Multi-Detection Capability | In stand-alone CE mode, UV/VIS, PDA, or LIF detection can be selected |
| Multiple Injections from Precious Samples | Sample analysis from as little as 5 μL |
The CESI 8000 Plus high-performance system delivers fast, efficient and unique separation selectivity with enhanced sensitivity, while simultaneously expanding coverage.
CESI-MS allows for a more robust system with ultra-low-flow < 10 nL/min, into the mass spectrometer resulting an overall increase in ionization efficiency.
| Specifications | |
|---|---|
| Dimensions | 29.2 in (74.2 cm) H x 25 in (63.5 cm) W x 28.4 in (72.1 cm) D |
| Portable Lab Bench | 36 in x 30 in (91.4 cm x 76.2 cm) Height adjusts 27 in to 44 in (69 – 112 cm) |
| Weight (uncrated) | 188 lbs (85.3 kg) |
| Electrical Requirements | Voltage: 100 – 240 V; 50/60 Hz |
| Sample Trays | 2 x 48 CESI vials / 0.3 mL microvials |
| Buffer Tray | 2 x 36 CESI vials |
| Pressure Delivery Range | -5 to +100 PSI |
| Required Sample Volume | 5 μl when using NanoVias |
